Sperm DNA fragmentation decreases the pregnancy rate in an assisted reproductive technique

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Sperm DNA fragmentation decreases the pregnancy rate in an assisted reproductive technique.

BACKGROUND Standard sperm characteristics are poor predictors of the outcome of IVF treatments. On the contrary, sperm genome quality has been emphasized for several years as playing a major role in early embryogenesis, thus in the success of IVF attempt. METHODS Sperm DNA fragmentation from a selected group of 104 couples undergoing assisted reproductive techniques (ART) (IVF: n = 50; and IC...

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The possession of offspring is the most important human biological goal, which conditions the survival of the human species. The problem of the lack of offspring is a phenomenon concerning approximately 15% of married couples in Poland. In a half of the cases, the causative agent is the male factor infertility problem. It is considered that in approximately 20% of patients with idiopathic infer...

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The Effect of Intercourse around Embryo Transfer on Pregnancy Rate in Assisted Reproductive Technology Cycles

Background Implantation failure is the most important cause of recurrent in vitro fertilization/intra cytoplasmic sperm injection (IVF/ICSI) failure. Several reports suggest that intercourse during the peritransfer period might improve pregnancy rates. This study is designed to determine whether intercourse during the peritransfer period will improve pregnancy and implantation rates in patients...

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ICSI significantly improved the pregnancy rate of patients with a high sperm DNA fragmentation index

OBJECTIVE Correlations between semen parameters and sperm DNA fragmentation index (DFI) were investigated to identify characteristics of sperm without DNA damage that could be used in selecting sperm for intracytoplasmic sperm injection (ICSI). Pregnancy outcomes were compared to determine whether in vitro fertilization (IVF) or ICSI is a better choice for patients who have sperm with a high-DF...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2003

ISSN: 1460-2350

DOI: 10.1093/humrep/deg228